LSD is a potent hallucinogen that alters perception, mood, and thought. People often call it “acid.” This mind-altering substance causes vivid sensory distortions. Users may see, hear, or feel things that do not exist. Its effects are unpredictable and depend heavily on “set and setting”—the user’s mindset and environment. Therefore, the same dose can produce vastly different experiences for different people. Swiss chemist Albert Hofmann first discovered its hallucinogenic effects in 1943.

History and Research
During the 1950s and 60s, researchers studied LSD for therapeutic uses and psychological insight. This research largely halted after it became a Schedule I controlled substance. However, recent clinical trials have revived interest in its medical potential. A typical dose (75–150 µg) produces effects lasting 6 to 12 hours. The experience can range from euphoria to intense fear. Consequently, users must approach it with caution and respect.

Risks and Precautions
LSD carries significant psychological risks. Users can experience terrifying “bad trips.” Long-term issues like flashbacks (HPPD) can also occur. While not physically addictive, it quickly builds tolerance. For this reason, frequent use becomes ineffective. Recent studies show serious adverse events are rare under medical supervision. Nevertheless, participants with pre-existing psychiatric conditions have experienced severe reactions. Thus, unsupervised use remains dangerous.

LSD (Lysergic acid diethylamide)

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